January-March 2018

Study of Epidemiological and Clinical Profile of Influenza A H1N1 Cases

Roshni Patel1*, Falguni Chavada2, Anand Suthar3

1Microbiology Department of and 2,3Medicine Department of, GMERS Medical College, Himmatnagar


BACKGROUND: Influenza virus is a common respiratory pathogen .In April 2009, a new strain of Influenza virus A H1N1 was evolved and spread in several countries around the world and caused pandemic. After that the resurgence of H1N1 epidemic occurs almost every year and it has caused significant morbidity and mortality. The objective of this study is to analyze the epidemiological profile, clinical characteristics and outcome of hospitalized H1N1 cases during 2015 epidemic. METHODS: The retrospective study of the category C H1N1 positive influenza cases admitted during 15 February 2015 to 25 March 2015 was done to analyze the epidemiological and clinical data. The statistical analysis was done by using Microsoft excel and chi square test RESULTS: Total 50 cases were studied. Female to male ratio was 1.5:1 with female preponderance and median age was 46 years. The most common presenting symptoms were cough, breathlessness, sore throat and fever. The case fatality rate was 14%. CONCLUSION: Our study shows higher age group shift of H1N1 cases compared to previous years. Total WBC counts were in lower range of normal limit. Co-morbid conditions were significantly associated with increase requirement for ventilatory support and need for ventilatory care was associated with significantly increased mortality.

Keywords: Clinical characteristics, epidemiological, H1N1 influenza epidemic

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