January-March 2018

Prevalence and Trends of Transfusion Transmitted Infections Among Blood Donors of Blood Bank Attached to Government Hospital, Vadodara

Jhalak Patel1*, Milind Dighe2, Farzana Kothari3, Swati Patel4

12nd Year Resident in IHBT, 2Head of Department, 3Associate Professor, 4Assistant Professor Department of Immunohematology and Blood Transfusion; S.S.G Hospital, Baroda.


BACKGROUND: Blood transfusion is life saving measure in emergencies and is important for the medical treatment of every patient; but it is never risk free. It always carries a potential risk of transfusion transmitted infections. The risk of transfusion transmitted infections is estimated to be 1 in 66,77,000 units for HIV; 1 in 1,03,000 units for hepatitis –C and 1 in 63000 units for hepatitis-B magnitude varies from country to country. OBJECTIVE: To assess the prevalence and trends in transfusion transmitted infections among blood donors in blood bank attached to government hospital, Vadodara. MATERIALS AND METHOD: A retrospective study of record covering the period of Jan-2014 to June-2016 was done in present study. All samples were screened by 3rd generation ELISA method for HIV1-2, HBsAg, HCV; screening for syphilis by Rapid Plasma Reagent and Malaria is done by peripheral smear. RESULT: Out of 29750 overall seroprevalence was 596 (2%). Out of 596; 41 (0.13%) reactive for HIV; 302 (1.01%) reactive for HBV; 173 (0.58%) reactive for HCV; 80 (0.26%) reactive for syphilis and 0 (0%) reactive for malaria. CONCLUSION: With implementation of strict donor criteria and use of sensitive screening tests it may be possible to reduce the incidence of transfusion transmitted infections in Indian scenario.

Keywords: Seroprevalence, HIV, HCV, HBsAg, Syphilis, Malaria, Blood donors.

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