January-March 2018

A Study on Clinical Profile & Prognostic Indicators in Patients with Acute Poisoning

Gosai. Kanugir. R1*, Gosai. Jigarkumar. B2

1M.D.Medicine, Assistant Professor, Department Of Medicine, Gmers Medical College, Gotri, Vadodara, 2M.D. Anaesthesia, Assistant Professor, Department Of Emergency Medicine, B.J.Medical College, Ahmedabad.


BACKGROUND: Organophosphoruspoisoning is associated with significant morbidity and mortality in developing countries. This study was done to study common clinical profile & predictors for poor prognosis in these patients. MATERIALS AND METHODS: Patients admitted to tertiary care centre between the November 2013 and November 2014, with history of organophosphorus poisoning werestudied, with preformed proforma. Data analysis was done with the help of computer using SPSS 17.0. RESULTS: Out of 50 patients included in the study, majority were male (80%)& highest 46% in between the age group of 21-30 years. Most common cause was suicidal (97.5%), commonly affecting illiterates& primary school educated people (42.5%) and from rural area (72%). Most common compound was organophospherous (66%) followed by ratkiller (24%). Most common finding abdominal pain (88%),vomiting (70%) followed by altered sensorium (36%). Higher mortaitywas associated with S.cholinesterase level <2000 IU/Lt on admission (P value: 0.0001)& interval >6 hours between ingestion and admission(P value:0.0289). CONCLUSION: Organophosphorus poisoning has become a common mode of suicide among developing countries. The ease of availability of the poison and the poor health carefacility has caused a higher mortality rate.

Keywords: organophospherous poisoning, clinical profile, prognostic predictors

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