JOURNAL COVER PAGE
 
 
 
 
VOLUME 6, ISSUE 4
October - December
 
Abstract

A Comparative Study of Metabolic Syndrome Among Diabetic & Non-Diabetic Patients

Deepak Kumar V1, Kotresh Doddamane2*, Adarsh V B3

1Assistant Professor, Department of General Medicine, Shantiram Medical College, Nandyal, India.

2Associate Professor, Department of General Medicine, Gadag Institute Of Medical Sciences, Gadag-582103,Karnataka

3Assistant Professor, Department of General Medicine, ESIC Medical College, Gulbarga

ABSTRACT

BACKGROUND: Metabolic syndrome encompasses a set of condition of which obesity in particular visceral obesity is an important component. Obesity has positive correlation with incidence and severity of diabetes. The risk of Type 2 Diabetes mellitus has been shown to rise markedly with increase in degree of obesity. AIM: The present study was conducted to compare the incidence of metabolic syndrome in diabetic and non-diabetic subjects. MATERIAL AND METHODS: The study included 100 subjects, of whom 50 were non-diabetic and 50 were diabetic patients. The subjects were studied by detailed history taking, clinical examination, anthropometric measurements and relevant investigations using a proforma specially designed for this study. The study group was matched with the Age, Gender &Body mass Index, to compare the important variables. Relevant Statistical analysis was done. RESULTS: Study shows that the incidence of metabolic syndrome in diabetic subjects is positively associated with increasing age. The incidence of Metabolic Syndrome in diabetic subjects was found to be high i.e, 70%, which is statistically significant when compared to non-diabetic subjects i.e, only in 26%. Over 90.9% diabetic subjects with duration of diabetes >5 years had metabolic syndrome. On the other hand only 53.5% of subjects with a duration of diabetes <5 years had metabolic syndrome. Hypertension was found to be more prevalent in diabetic subjects with metabolic syndrome i.e, 70%. In the diabetic subjects with metabolic syndrome all 100% had raised triglyceride & LDL levels and 66.7% had low HDL levels. The BMI of ≥25 kg/m2 was found in 70% of diabetic subjects with metabolic syndrome whereas in non-diabetic subjects with metabolic syndrome, it was only 27.6%.In our study, raised waist circumference in diabetic subjects with metabolic syndrome was found to be in 70%, whereas in non-diabetic subjects with metabolic syndrome the waist circumference was found to be raised in 86.7%. Insulin resistance was found in all 100% subjects with metabolic syndrome among diabetic & non-diabetic groups. CONCLUSION: In this study, the incidence of Metabolic Syndrome in diabetic subjects was found to be high which is statistically significant when compared to non-diabetic subjects.

Keywords: Metabolic syndrome, Diabetes mellitus, Insulin Resistance, Obesity


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