JOURNAL COVER PAGE
 
 
 
 
VOLUME 6, ISSUE 4
October - December
 
Abstract

Study of serum zinc and copper levels in hyperthyroid patients

Vikas k vaghela1*, Asha khubchandani2, Bhavika k vaghela3

1Resident Doctor, 2Associate Professor, Department of Biochemistry, 3Associate Professor, Department of Pathology, B.J. Medical College, Civil Hospital, Asarwa, Ahmedabad, Gujarat, India

ABSTRACT

BACKGROUND: The objective of this study is to analyse levels of trace elements in hyperthyroidism. The contents of the trace elements (Zn, Cu) in the serum of patients was determined and compared to that of normal subjects. METHODS:  Serum sample of 50 patients of known case of hyperthyroidism and normal subjects were taken. Serum Zinc and serum copper were estimated by spectrophotometric method in Fully automated  Erba XL-640 Analyzer. RESULT: In the current study there is significant rise in copper concentration and decrease in zinc concentration in serum of hyper thyroid patients compared to that of normal group (P value <0.05). CONCLUSION: As hormones influences trace element metabolism at several levels of actions including excretion and transport of trace metals. So trace elements assay can be used as diagnostic / prognostic help with other biochemical parameters in patients with different hormonal disorders.

Keywords: ZINC , COPPER , HYPERTHYROID


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