January-March 2018

A Study of Clinical and Investigative Profile of Malaria and Hepatitis E Virus Infection in Patients of Fever with Jaundice

Dhruv P Mehta1*, Mahendra C Parmar2

1Senior Resident, 2Additional Professor, Department of Medicine, Baroda Medical College and S.S.G Hospital, Vadodara, Gujarat


BACKGROUND: To study clinical manifestations, biochemical investigations and complications of malaria and Hepatitis E, alone and in coexistent infection. MATERIALS AND METHODS: The present study was conducted on 100 patients, of both malaria and Hepatitis E, admitted in SSG Hospital, Vadodara. This was an observational clinical study; both retrospective and prospective. RESULTS: Maximum patients of both infections were in age group 21-40 years. Males were affected more commonly than females in malarial group while females were affected more commonly than males in HEV positive group. All patients of coexistent malaria and HEV infections were females. Maximum patients in malaria group were positive for Plasmodium vivax. The most common presenting symptom in malaria group was fever while it was yellowish discoloration of urine and eyes in HEV. On clinical examination, most common finding in malaria, Hepatitis E and coexistent infection group was icterus. Maximum patients in malaria group had thrombocytopenia while all patients had normal platelet counts in HEV group.

Keywords: Malaria, Hepatitis E, coexistent, fever, icterus

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