A Study of Clinical Significance of HbA1c In Acute Myocardial Infarction

Ujval Patel1, Vitan Patel2, Ajay Dabhi3, Harikruhna Prajapati4, Ami Jhala4, Jayshree Gamit4

1MD Medicine Post graduate, 2Assistant Professor, 3Associate Professor, 4MD scholar, Department of Medicine, Government Medical College & S.S.G. Hospital, Vadodara, India.


BACKGROUND AND OBJECTIVES: Our study was performed in 100 patients, divided into two groups – Diabetics and non-Diabetics, to analyse the significance of HbA1c in patients with acute Myocardial Infarction. Study was concentrated on how two groups with different average HbA1c presented with regards to various complications of acute MI. To study To determine level of HbA1c in patients with acute myocardial infarction in both groups of patients (Diabetics and Non-Diabetics) and 2) Prospective observation of outcome in form of severity and complications in patients admitted with acute myocardial infarction in group A & group B. METHODS: Total 100 patients with acute MI were observed during this study, 52 of which were Diabetics (Group A) and 48 were Non-Diabetics (Group B). HbA1c levels were done in all patients and patients were observed for outcome in form of severity and complications. RESULTS: Group A patents (Diabetics), the ones with high HbA1c levels, had a significantly higher incidence of complications of acute MI, even death, when compared with group B non-diabetics with lower HbA1c. Even among group B patients without overt Diabetics, average HbA1c was higher than normal. CONCLUSION: We conclude at the end of this study that there is a strong correlation between HbA1c levels and various complications associated with acute myocardial infarction. There is also a significant correlation of mortality due to acute MI and HbA1c levels. We conclude that HbA1c might be considered a marker for prognosis for acute MI patients.

Keywords: Diabetes, Hba1c, Acute Myocardial infarction, complication of AMI.

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