JOURNAL COVER PAGE
 
 
 
 
VOLUME 7, ISSUE 1
January-March 2018
 
Abstract

Demographic profile of syphilis among blood donors at a tertiary care hospital

Yesha Shah1,Farzana Kothari3, Milind Dighe2, Chirag Chaudhari4

1 2nd Year Resident in Immunohaematology and Blood Transfusion . 2Head of the Department of Immunohaematology and Blood Transfusion. 3Associate Professor in Immunohaematology and Blood Transfusion. 4 Incharge blood bank, Bhailal Amin General hospital ,Vadodara. Department of Immunohaematology and Blood Transfusion, S.S.G Hospital, Baroda.

ABSTRACT

BACKGROUND AND OBJECTIVES: Syphilis is a sexually transmitted disease (STD) caused by Treponema pallidum , which can also be transmitted via accidental direct inoculation , transplacental during pregnancy , and, rarely, via blood transfusion. Although the value of routine serologic screening of blood donors for syphilis has been a question in debate for years as refrigerated blood components are less infective for syphilis. Transmission through blood components still occur therefore syphilis is included as one of the mandatory transfusion transmissible infection to be tested in any unit of blood for transfusion. This study was carried out to determine the prevalence of syphilis among blood donors in vadodara. METHODS: A 5 year Retrospective study was carried out at Department of Immunohaematology and Blood Transfusion of Govt Medical College, Baroda from April 2012 to March 2017. Before donation each potential donor was made to fill a detailed health history questionnaire, which included data regarding age, gender, address, occupation and other questions concerning the donor’s general health, lifestyle and risk behavior. All the donors were tested for syphilis using RPR test. RESULTS: Data for analysis included a total of 42,266 valid blood donation, out of which 187(0.44%) were found to be seropositive. Voluntary and replacement donors were 30,737(72.7%) and 11,529(27.2%) respectively. Out of which 98(0.31%) of voluntary and 89(0.77%) of replacement donors were found seropositive. The age group among donors with maximum seropositive rate was 30-39 years with prevalence rate of 38.24% and minimum in donors <20 years. The rates were found to be high among labourers (27.8%). 11 cases of co infection were noted. 7 with Hepatitis B, 2 with HIV and 2 with Hepatitis C. 74.2 % seropositive donors had educational qualification of middle school or less. CONCLUSION: Prevalence of syphilis among blood donors was in raising trends in this region and was more in replacement donors. It is equally more prevalent in middle aged individuals. It is more commonly present in labourers which may be attributed to high risk behaviour of these individuals. Most common co infection was Hepatitis B. Proper counseling prior to blood donation and awareness about syphilis among blood donors may increase the safety of blood as well as community.

Keywords: Syphilis, Sero-Positive , Replacement donors


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