April - June 2019

Prospective Study of Gastrointestinal Tract Lymphoma

Patel Harshadkumar Prahladbhai1, Patel Avani Mitesh2*, Patel Mitesh Himmatbhai3, Patel Maheshbhai K4

1Assistant Professor in General Pathology, Government Dental College & Hospital, Ahmedabad
2 Tutor in General Pathology, Government Dental College & Hospital, Ahmedabad
3Associate Professor Microbiology, M & J Institute of Ophthalmology, B J Medical College, Civil Hospital, Ahmedabad
4Professor in General Pathology, Government Dental College & Hospital, Ahmedabad


BACKGROUND AND OBJECTIVES: BACKGROUND: Gastrointestinal tract is the most frequently involved extra nodal site by lymphoma and it accounts for 4% to 20% of all non Hodgkin’s lymphoma or 30% to 40% of all extra nodal non Hodgkin’s lymphoma and second most common malignancy after adenocarcinoma. MATERIALS AND METHODS: Thirty five patients with histologically proven primary gastrointestinal lymphoma were studied with a special reference to their clinical features, mode of presentation, stage of disease and histopathological pattern of disease. RESULTS: Total 35 cases of GI lymphoma were studied. Twenty six cases of primary GI lymphoma were detected among 372 new cases of malignant lymphoma. Peak age incidence was found in second decade of life (12 patients, 34.2%) followed by fifth (9 patients, 25.7%), third (4 patients, 11.4%) and fourth decade. There was a preponderance for males in all sites of GI tract, overall male : female ratio was 1.7:1. Stomach is the most frequently involved site (15 patients-43%), followed by small intestine (14 patients: 40%), large intestine (5 patients-14.2%), ileocaecal (1 patient-2.8%). CONCLUSION: Incidence of primary GI lymphoma was 6.98 % with median age was 31 years, male preponderance and stomach is the most common site for GI lymphoma

Keywords: Extranodal, Non Hodgkin’s lymphoma, GI tract.

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