January - March 2021

Prevalence Of Diabetes Mellitus In Active Pulmonary Tuberculosis Patients And Clinico-Radiological Presentation Of Tubercular Diabetic Patients.

A. B. Srivatava1, Priyank Jain2*, Sanjay Jain3

1MD, Professor, 2MBBS, 3rd year PG resident,3MBBS, MD, Department of Respiratory Medicine, R.N.T Medical College, Udaipur, Rajasthan, India.



BACKGROUND: Association between tuberculosis and diabetes mellitus is known since ancient times. Tuberculosis is more frequent (four to five times) among diabetics but there are conflicting views on increased prevalence of diabetes & prediabetes in tuberculosis patients. Presently developing nations are facing epidemic of both diseases. It becomes important to screen diabetes mellitus among tuberculosis patients as both diseases have adverse effects on each other outcomes. AIMS AND OBJECTIVES: To detect prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in patients with active pulmonary tuberculosis and to correlate these patients with presentation of tuberculosis. MATERIAL AND METHODS: A cross-sectional study was carried out in 146 patients of active pulmonary tuberculosis. Their fasting plasma glucose & oral glucose tolerance test were performed after withdrawal of known diabetogenic and anti TB treatment was started immediately thereafter. Known diabetics excluded from study population. RESULTS: 8.2% & 12.3% patients had diabetes & prediabetes respectively. Prevalence of TB diabetics increases with age and was more in males compared to females. TB diabetics had more symptoms and far advanced disease which were statistically significant. CONCLUSIONS: TB diabetic patients have more symptoms but symptoms of pulmonary tuberculosis are not different from non diabetic TB patients, no other radiological presentation except of extent of disease are significant. Majority of TB diabetics have far advanced disease and grade 3 sputum positivity. Hence pulmonary tuberculosis patients should have screening for diabetes mellitus particularly if they have such presentation.

Keywords: pulmonary tuberculosis, diabetes mellitus, prevalence.


Keywords: Radiological Presentation Of Tubercular Diabetic Patients.

[Full Text Article]