January - March 2021

Study of Intra Ocular Pressure changes after  ND:YAG LASER Capsulotomy in Patients with Pre Procedure Timolol(0.5%) eyedrop and without Timolol (0.5%) eyedrop.

Parth leuva1*, Nilesh Parekh2, Shankar Ganvit3, Niyant Pandya4

1Senior Resident Doctor, 3Associate Professor,4Professor  and Head, Department of Ophthalmology, S.S.G. Hospital and Medical College, Vadodara.2Professor and Head, Department of Ophthalmology, Sir T Hospital and Medical College, Bhavnagar



BACKGROUND: To study  the efficacy of pre procedure topical Timolol(0.5%)eyedrop in preventing post procedure Intraocular pressure(IOP) rise in eyes undergoing ND:YAG CAPSULOTOMY. MATERIALS AND METHODS:  A Prospective Open Labelled Randomised Comparative study conducted in 50eyes, over a period of 5months.Pre capsulotomy baseline IOP by Goldmann Applanation Tonometer (GAT) , Slitlamp Examination, Dilated fundus Examination, Best corrected visual acuity testing was done.After instilling a test medication ND: YAG CAPSULOTOMY  performed. Post capsulotomy patients were assessed immediately,  1 hour, 24 hour, 48 hour, 1 week, 2 week for IOP. RESULT : Precapsulotomy, mean IOP in group A ( use of pre procedure timolol eyedrop ) was 12.88±2.011 mmHg as compared to 13.96±2.26 mmHg in group B ( without pre procedure timolol eyedrop ). However  after capsulotomy mean IOP at 1hour in group A was 13.08±3.06 mmHg as compared to 14.48±1.96 mmHg in group B which was statistically not significant . 24 hour and 2 week after  the procedure too, mean IOP in group A and B shows statistically no significant difference. CONCLUSION: According  to all data the study shows that there was  some drop in IOP occurs in group A  2  days after capsulotomy  suggestive of some effectivity of Timolol but it was not significant  there was no any significant difference in mean IOP in both group in rest of the  time interval after ND:YAG LASER capsulotomy , so it suggest that there is some  role of prophylactic use of timolol 0.5% eyedrop for controlling IOP changes occuring  within 3 day after ND:YAG laser capsulotomy. IOP changes are not significant may be due to small sample size , person to person diurnal variability in IOP, variable amount of laser energy and number of laser shots applied to remove posterior capsular opacification person to person.


Keywords: Intraocular pressure (IOP), ND:YAG LASER capsulotomy, Posterior Capsular Opacification (PCO), Timolol, Goldmann Applanation Tonometry ( GAT).ND:YAG ( neodymium-doped yttrium aluminium garnet) laser.


Keywords: YAG LASER Capsulotomy in Patients with Pre Procedure Timolol

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