January - March 2021

Clinical profile of Sickle Cell Disease patients coming to a tertiary care hospital from central Gujarat

Keyur Brahme1, Kedar Mehta2*, Kalpita Shringarpure3, Mahendra Parmar4

1MD (Medicine) Assistant Professor, 4MD Associate Professor, Department of Medicine, Baroda Medical College, Vadodara, 2MD (PSM), DMCH, CNM, CIH, Assistant Professor, Dept. of Community Medicine (PSM), GMERS Medical College, Gotri, Vadodara, 3MD (PSM), DPH, PGCNM, MBA, Tutor, Department. of Community Medicine Baroda Medical College, Vadodara.



BACKGROUND AND OBJECTIVES: The situation of the hereditary hemoglobinopathies including sickle cell disease (SCD) is very grim in India as well as in Central Gujarat. So to study the regional diversity in hemoglobin variants prompted us to look at the clinical profile of patients presenting with this condition. METHODS: This was a cross sectional study involving a total of 41 patients with sickle cell diseases over a period of two years attending tertiary care government hospital in Vadodara, Central Gujarat. The data was entered in Microsoft excel sheet and analysis was done using Epi Info software. RESULTS & CONCLUSION: Among the 41 study participants having SCD, we found that 23 were males and 18 were females. The mean age of patients was 22.4 years. The common presenting symptoms include arthralgia, bodypain, abdominal pain, breathlessness, fatigue and edema. The mean BMI of the patients of SCD was 20.36 kg/m2 and their average duration of hospital stay was 6.3 days. Almost all (40) patients were discharged and one patient died due to severe complications of vasoocclusive crisis.


Key words: Sickle cell disease, clinical profile, Gujarat

Keywords: Clinical profile of Sickle Cell Disease patients

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